Lamarck's Signature

by Robert V. Blanden, Edward J. Steele, Robyn A. Lindley

Oct 7, 1999
Paperback
US $15.50
ISBN: 9780738201719
ISBN-10: 0738201715
Published by Basic Books

 

Description

This controversial book challenges the accepted theories on the genetic mechanism of evolution. The story these three biologists have to tell may very well upset the whole field of biology. The traditional view of evolution—which grew out of the work of Gregor Mendel and Charles Darwin and is strongly supported by present-day scientists like Richard Dawkins and Stephen Jay Gould—assumes we are at the mercy of our genes, which we inherit largely unchanged from our parents, except for rare random mutations which accumulated and lead to change over evolutionary time. Those genes are coded in the chromosomes of the sperm and egg cells of the parents, and so only changes to those two types of cell have any chance of being passed down to the parents'’ offspring. Any changes, accidents, or surgery to the rest of the parent’s bodies are not transmitted to the newborn. The theory of inheritance of acquired characteristics—if you build up your muscles your kids will be born with a propensity toward great strength—on the other hand, favored by Jean Lamarck in the nineteenth-century, was brought down by nineteenth-century science. But now, as this challenging and thrilling book shows, it looks as though, at least for certain structures in the body’s immune system, Lamarck may have been right after all. Based on their own ground-breaking work over the past two decades, as well as that of other molecular biologists, Steele, Lindley, and Blanden argue that for one adaptive body system there is strong molecular genetic evidence that aspects of acquired immunities developed by parents in their own lifetime can be passed on to their offspring. Certain to stimulate lively debate, Lamarck’s Signature gives new life and scientific credibility to the Lamarckian heresy—the notion of the inheritance of acquired characteristics.

Reviews


”It will represent, indeed, one of the landmarks in the history of biology. I have no idea what the outcome will be but I hope Steele is right.
— Sir Peter Medawar

”If the work of Ted Steele and his colleagues…is correct, then the immune system is violating one of the central tenets of modern Darwinian evolutionary theory.”
New Scientist

”It has been a dogged effort punctuated by bruising encounters with the British scientific establishment…between the brickbats and bouts of controversy, twenty years of single-minded research seems finally to have paid off for Ted Steele.”
The Australian

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